What are the main causes of female fertility problems?


Age plays a very vital role in conceiving a baby. For couples who are under 30 & generally healthy, can conceive in the first three months of trying. After the age of 30, a woman’s chance of conceiving gets very low & starts dropping with each passing year. If someone is facing issues related to conceiving or wants to educate themself relating to infertility, they should see a doctor. That will the best source of answer & will be accurate too. Many women may be unaware of the fact that lifestyle choices can affect women’s chances of getting pregnant.

If you are hoping to have a baby, you might take steps to improve your fertility. But remember, there are some factors that might be beyond your control & you will have to visit an IVF Clinic in Mumbai. Female fertility is a woman’s ability to conceive a biological child. You and your partner might question your fertility if you’ve been trying to get pregnant with frequent, unprotected sex for at least one year — or at least six months if you’re older than 35 — with no success.

There are various medical issues that can contribute to female fertility issues:

  •  Ovulation disorders, affect the release of eggs from the ovaries. These include hormonal disorders such as polycystic ovary syndrome, hyperprolactinemia, and thyroid problems (hyperthyroidism or hypothyroidism).
  • Uterine or cervical abnormalities, such as polyps or fibroids in the uterus.
  • Fallopian tube damage or blockage is often caused by pelvic inflammatory disease.
  • Endometriosis occurs when tissue that normally lines the inside of the uterus grows outside the uterus.
  • Primary ovarian insufficiency (early menopause), occurs when the ovaries stop working and menstruation ends before age 40.
  • Pelvic adhesions — bands of scar tissue that bind organs after pelvic infection, appendicitis, or abdominal or pelvic surgery.
  • Medical conditions associated with the absence of menstruation, such as poorly controlled diabetes, celiac disease, and some autoimmune diseases such as lupus.


DR L H Hiranandani hospital has been ranked among the top IVF Clinic in Mumbai & provides various IVF treatments which have been proven to be successful over the years.

Best IVF Treatment in Powai

With many successful IVF patient stories, we are dedicated to serving more patients at our IVF clinic in Powai


Our IVF treatments

Best IUI Clinic in Mumbai

Intra-Uterine Insemination (IUI) is a process in which washed sperms are placed directly into the uterus with the help of a thin catheter. IUI treatment is an OPD (out-patient department) procedure. Neither anesthesia nor hospitalization is required for IUI. Ovulation is verified by USG. After the confirmation, the partner is required to collect semen in a sterile container. It takes approximately 45 minutes to an hour to prepare the semen sample. A small tube called an IUI catheter is carried in the uterus & the processed semen sample is smoothly released in the uterus. Luteal phase support is given and pregnancy is confirmed fifteen days following by a simple blood test. Dr L H Hiranandani has been serving many patients with IUI treatments & has successfully got great results.

Best IVF/ICSI Treatment in Mumbai

IVF stands for In Vitro Fertilization. It is the process by which a woman’s eggs are gathered and then fertilized outside her womb in the lab. ICSI (Intracytoplasmic Sperm Injection) has proved to be very useful in couples who have failed to accomplish fertilization or had very poor fertilization following standard IVF treatment & in couples where the male partner has irregular sperm parameters (e.g. low count, poor motility, a high percentage of abnormal sperms). The IVF / ICSI procedures do not require overnight hospitalization. Dr L H Hiranandani hospital is being ranked as the best ICSI center in Mumbai with many successful patient stories

Donor Egg Program

At Dr L H Hiranandani hospitals egg donation center in Mumbai, another woman is the egg donor. The donor is chosen after a detailed medical evaluation and relevant investigations reveal normal results. The donor undergoes IVF stimulation followed by ovum pick up. The donor’s eggs are generated with the recipient’s husband’s sperm. The resultant embryos are then shifted in the suitably prepared uterus of the recipient.

Best Surrogacy center in Mumbai

In cases where the uterus is distorted or damaged and is inadequate of carrying a pregnancy, multiple miscarriages have occurred, a pregnancy would be life-threatening, surgical elimination of the uterus has been undertaken due to cancer, the womb has broken or the individual was born without a uterus, surrogacy is indicated. The term Surrogacy is used when a female womb carries a baby and gives birth to a baby for another woman. The Surrogate carries the pregnancy and is genetically not linked to the child.

IVF Center in Mumbai

At our IVF Center in Mumbai, we use the following latest techniques to improve pregnancy rates:

Blastocyst Transfer

A blastocyst is the final stage of the embryo’s development before it hatches out of the shell (zona pellucida) and implants in the uterine wall. Studies suggest that transfer of the embryo on day 5, at the blastocyst stage, yields a higher pregnancy rate.

Laser Assisted Hatching

Assisted hatching is performed in the laboratory just prior to embryo transfer. It is a simple and precautionary procedure where a small hole is made in the outside shell (the zona) of each embryo to be transferred.

Subendometrial Blood Flow

Low implantation rates in stimulated IVF cycles may be related to suboptimal endometrial perfusion. This can be easily diagnosed by a non invasive test like a sonography with a Doppler ultrasound. This poor blood flow can be then be improved by alteration in medications and the pregnancy rates can be improved.

PICSI (Physiological ICSI)

PICSI sperm selection device is now available for the selection of mature sperms for ICSI. These selected sperms will have minimal DNA fragmentation, normal shape and low frequency of chromosomal aneuploidies improving the pregnancy rate and also reducing the rate of abortions.

Growth Hormone Therapy

Growth Hormone therapy is an adjuvant treatment used in ovarian stimulation and ART. Growth Hormone supplements have shown to improve pregnancy rates in poor responders.

Preimplantation Genetic Screening (PGS)

PGS is used to test whether embryos (obtained through IVF/ICSI) have an abnormal number of chromosomes.

GCSF (Granulocyte Colony Stimulating Factor) Infusion

G-CSF is a cytokine/growth factor crucial for implantation. It is used for implantation failure, recurrent abortions, and thin endometrium which fails to respond to standard therapy.

Platelet –Rich Plasma (PRP) Infusion

The endometrium is one of the main factors in implantation and pregnancy. Pregnancy rates rise with growing endometrial thickness. Intrauterine infusion of platelet-rich plasma (PRP) is a new approach that has been suggested for the treatment of a thin endometrium.

Preimplantation Genetic Diagnosis (PGD)

PGD is the testing of preimplantation stage embryos or oocytes for genetic defects. It has been developed for couples whose potential offspring are at risk of severe Mendelian disorders, structural chromosome abnormalities or mitochondrial disorders.

Fertility Enhancing Surgeries

 Laparoscopy and Hysteroscopy can be used for both diagnostic (looking only) and operative (looking and treating) purposes. Diagnostic laparoscopy may be recommended to look at the outside of the uterus, fallopian tubes, ovaries, and internal pelvic area. Diagnostic Hysteroscopy is used to look inside the uterine cavity. If an abnormal condition is detected during the diagnostic procedure, operative laparoscopy /  operative Hysteroscopy can  be performed  to correct it at the same time, avoiding the need for a second surgery. For Example in cases of hydrosalpinx (Diseased fallopian tube filled with fluid), pregnancy rate with IVF treatment and no surgery is 10.4% as compared to IVF treatment after laproscopic delinking of the tube (surgical procedure required for hydrosalpinx) which is 34.2 %. Similarly other procedures like hysteroscopic septum resection,hysteroscopic Adhesiolysis, laproscopic myomectomy can improve the pregnancy rate.

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