The Role of Genetic Testing in IVF: Screening and Testing Options


The Role of Genetic Testing in IVF

The fundamental objective of fertility care is to assist prospective parents in having a healthy pregnancy and birth that results in a child free of disease and genetic defects. Doctors at Best IVF Hospital in Mumbai recommend genetic testing and screening for the couple who is opting for IVF. Preimplantation genetic testing (PGT) is a cutting-edge reproductive treatment procedure that can be performed during IVF to help select the healthiest embryos and boost the odds of a successful pregnancy.

The working of Preimplantation Genetic Testing

Eggs are fertilized with sperm during IVF to make embryos. Embryos reach the blastocyst stage of embryonic development after five to six days, consisting of an inner cell mass and an outer layer of cells called the trophectoderm. PGT is removing a tiny sample from the trophectoderm in order to screen the embryo for genetic abnormalities or conditions. 

Types of Genetic Testing

There are various types of genetic testing services available for various scenarios. Some test only a few genes, while others examine the entire chromosome. Some researchers investigate enzymes, which are unique proteins. Physicians and genetic counselors assist families in selecting the appropriate test. Consider consulting an IVF expert at the Best IVF Center in Mumbai to select the suitable genetic test for you.

Preimplantation Genetic Testing for Aneuploidy / PGT-A

PGT-A, commonly known as preimplantation genetic screening, is the most prevalent type of embryo testing (PGS). This test determines whether an embryo has a normal or abnormal number of chromosomes, which can cause a variety of genetic problems if too many or too few are present. Chromosomal abnormalities are a prevalent cause of recurrent pregnancy loss, particularly in severe male factor infertility or in female patients over the age of 35. However, according to the doctors at the best IVF hospital in Mumbai, a new study has demonstrated that PGT-A results can occasionally yield false-positive results, and more research is being conducted in this area.

Preimplantation Genetic Testing for Monogenetic Disorders

PGT-M, commonly known as preimplantation genetic diagnostic (PGD), is a test that determines whether a specific inheritable disorder exists within a patient’s embryos. This form of genetic screening is advised when one or both couples have a family history of genetic disorders. PGT-M can screen for autosomal recessive, X-linked, and dominant disorders.

Preimplantation Genetic Testing for Structural Chromosomal Rearrangement

PGT-SR testing is used to detect a very specific form of chromosomal abnormality. This test is usually indicated for patients who have a history of recurrent pregnancy loss or other difficulties and have been identified with a chromosomal translocation. PGT-SR testing is the least prevalent type of testing, and patients usually receive genetic counseling before generating embryos for screening.

Preimplantation Genetic Testing at Dr L H Hiranandani Hospital

Dr L H Hiranandani Hospital has the best IVF Center in Mumbai that provides comprehensive care with a team of top IVF doctors. Contact Dr L H Hiranandani Hospital today if you are interested in IVF combined with genetic testing. We offer preconception counseling, which can include genetic testing, which is simple and only requires a blood sample or a cheek cell swab. We have assisted many families from Mumbai and other states of India as well.

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